All Research Areas
Metabolic ResearchResearch Grade

Metabolic & Weight Research

SURMOUNT trial data and metabolic research on tirzepatide's weight reduction mechanisms.

-22.5%
Body weight (Tirzepatide)
SURMOUNT-1, 15mg, 72 wks
-14.9%
Body weight (Semaglutide)
STEP-1, 2.4mg, 68 wks
57%
Lost ≥20% (Tirzepatide 15mg)
SURMOUNT-1 participants
≥98%
Purity guarantee
Third-party tested

Tirzepatide Metabolic Research

The SURMOUNT clinical trial program has produced the most impressive weight loss data of any peptide studied to date.

SURMOUNT Trial Results

TrialPopulationDoseDurationMean Weight Loss
SURMOUNT-1Obesity15mg72 weeks22.5%
SURMOUNT-2Obesity + T2D15mg72 weeks15.7%
SURMOUNT-3Intensive LI15mg72 weeks26.6%

SURMOUNT-1 highlights at 15mg:

  • 96% of participants achieved ≥5% weight loss
  • 91% achieved ≥10% weight loss
  • 57% achieved ≥20% weight loss

Comparison with Semaglutide

Direct comparison of phase 3 data (different trials):

  • Tirzepatide 15mg: 22.5% weight loss (SURMOUNT-1)
  • Semaglutide 2.4mg: 14.9% weight loss (STEP-1)
The SURPASS-CVOT cardiovascular outcomes trial is ongoing.
RESEARCH COMPOUNDS

Research-Grade Metabolic & Weight Research

>98% purity, third-party tested. Free shipping on orders over $200.

Frequently Asked Questions

How much weight loss in SURMOUNT?

SURMOUNT-1 showed 22.5% mean body weight reduction at 72 weeks with tirzepatide 15mg. SURMOUNT-3 with intensive lifestyle intervention showed 26.6%.

Is tirzepatide better than semaglutide?

Phase 3 data shows tirzepatide 15mg (22.5%) outperforms semaglutide 2.4mg (14.9%) for weight loss. However, direct head-to-head trial data is limited and semaglutide has more established cardiovascular outcomes data.

What is the best tirzepatide dose for research?

Research protocols typically start at 2.5mg/week and escalate to 5-15mg/week. The 15mg dose showed maximum efficacy in SURMOUNT trials.

Research-Grade Metabolic & Weight Research

Third-party tested, >98% purity guaranteed. For legitimate scientific research.

>98% Purity Research Grade Free Ship $200+